With the implementation of ready-to-use aseptic filling line, PSM has the capabilities of processing pre-sterilized syringes, vials and cartridges. The first cartridges were being filled for a small scale R&D application recently.
With e.g. the GLP1 insulin has been growing significantly over the last years, also the demand for filling capacities for pre-crimped cartridges for smaller batches has increased.
In the GMP lab scale, PSM can fill and close around 500 cartridges per day. In clinical phases 2 and 3, as well as in subsequent commercial manufacturing, up to 7,000 units per hour can be processed.
All Fill & Finish solutions can be executed with vacuum stoppering. This is extremely important, especially when a high stopper position accuracy is required and also if there is the requirement for a very low residual air bubble. Both parameters can be extremely important when using a pre-crimped cartridge in traditional pen technologies.
