{"id":12524,"date":"2025-01-20T12:24:01","date_gmt":"2025-01-20T11:24:01","guid":{"rendered":"https:\/\/psm-saar.de\/?page_id=12524"},"modified":"2026-02-13T12:14:36","modified_gmt":"2026-02-13T11:14:36","slug":"diluent","status":"publish","type":"page","link":"https:\/\/psm-saar.de\/en\/diluent\/","title":{"rendered":"Diluent"},"content":{"rendered":"<div class=\"gb-container gb-container-a579df3d\"><div class=\"gb-inside-container\">\n<div class=\"gb-container gb-container-cb1d4eec\">\n\n<h1 class=\"gb-headline gb-headline-1a6fe487 gb-headline-text\">Diluent filled in Vials, pre-filled Syringes (PFS), and Cartridges<\/h1>\n\n\n<div class=\"gb-grid-wrapper gb-grid-wrapper-d755006d\">\n<div class=\"gb-grid-column gb-grid-column-fd0e5481\"><div class=\"gb-container gb-container-fd0e5481\"><div class=\"gb-inside-container\">\n\n<p>A diluent is a substance used to dilute or dissolve another material, such as a drug or an active ingredient, safely and effectively. In pharmacology and biotechnology, a diluent is often used to adjust a concentrated drug to a concentration suitable for the body or to facilitate its administration.<\/p>\n\n<\/div><\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-60252454\"><div class=\"gb-container gb-container-60252454\"><div class=\"gb-inside-container\">\n\n<p>A diluent is par\u00adticularly important in the pre\u00adparation of injec\u00adtable or intra\u00advenously administered drugs that need to be converted from a powdered form (e. g., a lyophilisate) into a liquid form. In such cases, the diluent is used to dissolve the powder, enabling the medication to be injected or administered.<\/p>\n\n<\/div><\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"gb-container gb-container-e4bd32c0\">\n\n<figure class=\"wp-block-gallery has-nested-images columns-2 is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"400\" data-id=\"12634\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/01\/felxfill-aseptic-manufacturing-pharmaceutical-products-psm-1.jpg\" alt=\"\" class=\"wp-image-12634\" srcset=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/01\/felxfill-aseptic-manufacturing-pharmaceutical-products-psm-1.jpg 600w, https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/01\/felxfill-aseptic-manufacturing-pharmaceutical-products-psm-1-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"400\" data-id=\"14614\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/06\/products-psm-gruppe-02-1.jpg\" alt=\"PSM - aseptische Abf\u00fcllung Pharma CDMO\" class=\"wp-image-14614\" srcset=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/06\/products-psm-gruppe-02-1.jpg 600w, https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/06\/products-psm-gruppe-02-1-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n<\/figure>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-accent-2-color has-alpha-channel-opacity has-accent-2-background-color has-background\"\/>\n\n\n\n<div>\n<h2 class=\"wp-block-heading\">Our processes and equipent for diluents include:<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Use of all common pre-sterilized packaging materials, such as PFS syringes, vials, or cartridges<\/li>\n\n\n\n<li>Filling in a sterile Class A cleanroom using state-of-the-art Groninger filling technology<\/li>\n\n\n\n<li>Various pumping systems, stopper placement via vacuum or insertion tube, and optional gassing<\/li>\n\n\n\n<li>In-house terminal sterilization\u00a0<\/li>\n\n\n\n<li>Visual inspection, CCIT, and packaging<\/li>\n\n\n\n<li>Single-Use-Compounding mit einer Batchgr\u00f6\u00dfe von bis zu 600 L<\/li>\n<\/ul>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-accent-2-color has-alpha-channel-opacity has-accent-2-background-color has-background\"\/>\n\n\n\n<p>With the Groninger <strong>Flexfill filling system<\/strong>, we can fill batch sizes of up to 600&nbsp;liters. We offer maximum flexibility in processing ready-to-use syringes up to 50&nbsp;ml, vials up to 100&nbsp;ml, and cartridges up to 10&nbsp;ml in glass or polymer. This line is equipped with peristalitc and rotary piston pumps and various gassing and vacuum options.<\/p>\n\n\n<div class=\"gb-container gb-container-33e09a57\">\n\n<figure class=\"wp-block-video\"><video height=\"720\" style=\"aspect-ratio: 1280 \/ 720;\" width=\"1280\" controls poster=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/09\/psm-flexfill-video-fill-and-finish-services.png\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2026\/01\/PSM-flexfill-2026.mp4\"><\/video><\/figure>\n\n<\/div>\n\n\n<hr class=\"wp-block-separator has-text-color has-accent-2-color has-alpha-channel-opacity has-accent-2-background-color has-background\"\/>\n\n<\/div>\n\n<div class=\"gb-container gb-container-772bfa3b\"><div class=\"gb-inside-container\">\n<div class=\"gb-container gb-container-772bfa3b\"><div class=\"gb-inside-container\">\n\n<h3 class=\"gb-headline gb-headline-4eb99f69 gb-headline-text\">Our Services as an End-to-End Pharma CDMO<\/h3>\n\n\n<div class=\"gb-grid-wrapper gb-grid-wrapper-6a9f5337\">\n<div class=\"gb-grid-column gb-grid-column-f1a80c71\"><div class=\"gb-container gb-container-f1a80c71 kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-cdmo-deutschland\/api-manufacturing\/\" aria-label=\"More about our api manufacturing services\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-wirkstoff.png\" alt=\"\" class=\"wp-image-10115\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-5fb709cd\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-e28a1954 gb-headline-text\"><a title=\"\" href=\"https:\/\/psm-saar.de\/en\/pharma-cdmo-deutschland\/api-manufacturing\/\">API Manufacturing<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-c5a9fb3d\"><div class=\"gb-container gb-container-c5a9fb3d kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/formulation-development\/\" aria-label=\"Go to formulation and development\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-formulierungsentwicklung.png\" alt=\"\" class=\"wp-image-10121\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-04d8c970\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-ecc83657 gb-headline-text\"><a href=\"#\">Method and Process Development<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-d7793a7f\"><div class=\"gb-container gb-container-d7793a7f kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/analytik\/\" aria-label=\"Got to analytical services\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full is-resized kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-analytik.png\" alt=\"\" class=\"wp-image-10117\" style=\"width:200px\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-01eb533c\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-88da68ee gb-headline-text\"><a href=\"#\">Analytical Services<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-3c1bb04b\"><div class=\"gb-container gb-container-3c1bb04b kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/finished-medical-products\/\" aria-label=\"Go to aseptic filling services for clinical trials\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-klinische-muster.png\" alt=\"\" class=\"wp-image-10109\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-8e03e872\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-23351a9a gb-headline-text\"><a href=\"#\" title=\"\">Aseptic Fill &amp; Finish Services for Clinical Trials<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-db36bb92\"><div class=\"gb-container gb-container-db36bb92 kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/fill-finish-services-commercial\/\" aria-label=\"Go to aseptic filling services for commercial products\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2025\/11\/fill-and-finish-service-for-medicals.png\" alt=\"Pharmaceutical Fill and Finish Services\" class=\"wp-image-15984\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-35fd1dda\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-dc020a7a gb-headline-text\"><a href=\"#\">Aseptic Fill &amp; Finish Services for Commercial Products<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-d11449ec\"><div class=\"gb-container gb-container-d11449ec kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/packaging\/\" aria-label=\"Go to container closure integrity testing - CCIT\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full is-resized kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-optische.png\" alt=\"\" class=\"wp-image-10111\" style=\"height:110px\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-e68592e1\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-60b3a7b5 gb-headline-text\"><a href=\"#\">Visual Inspection and Container Closure Integrity Testing<\/a><br><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-7d2ad7eb\"><div class=\"gb-container gb-container-7d2ad7eb kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/packaging\/\" aria-label=\"Got to secondary packaging and labelling\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full is-resized kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-sekundaerverpackung.png\" alt=\"\" class=\"wp-image-10113\" style=\"width:200px;height:100px\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-189ea72d\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-8f90c8f7 gb-headline-text\"><a href=\"#\"> Secondary Packaging<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-982fe98c\"><div class=\"gb-container gb-container-982fe98c kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-cdmo\/gmp-storage\/\" aria-label=\"Go to gmp storage\" rel=\"nofollow\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><a href=\"https:\/\/psm-saar.de\/en\/pharma-cdmo\/gmp-storage\/\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-gmp-lager.png\" alt=\"\" class=\"wp-image-10107\"\/><\/a><\/figure>\n\n\n<div class=\"gb-container gb-container-6a95d4f3\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-22f65d01 gb-headline-text\"><a href=\"#\" title=\"\">GMP Storage<\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n\n<div class=\"gb-grid-column gb-grid-column-c361547a\"><div class=\"gb-container gb-container-c361547a kat-container\"><a class=\"gb-container-link\" href=\"https:\/\/psm-saar.de\/en\/pharma-dienstleistungen\/gdp-transports\/\" aria-label=\"Go to gdp transport\"><\/a>\n\n<figure class=\"wp-block-image aligncenter size-full kat-image\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"100\" src=\"https:\/\/psm-saar.de\/wp-content\/uploads\/2023\/06\/icon-gdp-transport.png\" alt=\"\" class=\"wp-image-10105\"\/><\/figure>\n\n\n<div class=\"gb-container gb-container-9aa7aa6d\"><div class=\"gb-inside-container\">\n\n<h4 class=\"gb-headline gb-headline-08890297 gb-headline-text\"><a href=\"#\">GDP Transport <\/a><\/h4>\n\n<\/div><\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Diluent filled in Vials, pre-filled Syringes (PFS), and Cartridges Our processes and equipent for diluents include: With the Groninger Flexfill &#8230; <a title=\"Diluent\" class=\"read-more\" href=\"https:\/\/psm-saar.de\/en\/diluent\/\" aria-label=\"Read more about Diluent\">weiterlesen &#8230;<\/a><\/p>\n","protected":false},"author":2,"featured_media":12563,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-12524","page","type-page","status-publish","has-post-thumbnail"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/pages\/12524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/comments?post=12524"}],"version-history":[{"count":6,"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/pages\/12524\/revisions"}],"predecessor-version":[{"id":16988,"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/pages\/12524\/revisions\/16988"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/media\/12563"}],"wp:attachment":[{"href":"https:\/\/psm-saar.de\/en\/wp-json\/wp\/v2\/media?parent=12524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}